127 research outputs found

    Experimental investigation of a confined, jet- driven water vortex

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    Effects on confined vortex flow produced by varying aspect ratio in gaseous core reacto

    Wind loading on solar concentrators: Some general considerations

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    A survey was completed to examine the problems and complications arising from wind loading on solar concentrators. Wind loading is site specific and has an important bearing on the design, cost, performance, operation and maintenance, safety, survival, and replacement of solar collecting systems. Emphasis herein is on paraboloidal, two-axis tracking systems. Thermal receiver problems also are discussed. Wind characteristics are discussed from a general point of view. Current methods for determining design wind speed are reviewed. Aerodynamic coefficients are defined and illustrative examples are presented. Wind tunnel testing is discussed, and environmental wind tunnels are reviewed. Recent results on heliostat arrays are reviewed as well. Aeroelasticity in relation to structural design is discussed briefly

    Heat transfer from partially ionized argon flowing in a conducting channel with an applied, transverse magnetic field

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    Transverse magnetic field effects on wall heat transfer from ionized argon channel flo

    A preliminary assessment of small steam Rankine and Brayton point-focusing solar modules

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    A preliminary assessment of three conceptual point-focusing distributed solar modules is presented. The basic power conversion units consist of small Brayton or Rankine engines individually coupled to two-axis, tracking, point-focusing solar collectors. An array of such modules can be linked together, via electric transport, to form a small power station. Each module also can be utilized on a stand-alone basis, as an individual power source

    Site-Specific Research Conducted in Support of the Salton Sea Solar Pond Project - FY 1982 Report

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    The design and operation of a salt-gradient solar pond power plant at the Salton Sea presents problems not encountered at small research ponds that were built in the United States. The specific characteristics of the Salton Sea site and the desire to construct the pond using the local clay as a sealant represent major deviations from previous solar pond experience. The site-specific research in support of the plant design is described. The research activity included validation of the spectrophotometric light transmission measurement technique, a search for options for clarifying the turbid and colored water of the Salton Sea, development of water clarification specifications in terms common to industry practice, quantification of gas production from microbiological reactions in the ground, a determination of the combined effects of temperature and salinity on the permeation of the local clays, and a preliminary evaluation of material corrosion

    An Experimental Investigation of Fluid Flow and Heating in Various Resonance Tube Modes

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    Experiments have been performed to study resonance phenomena in tubes excited by underexpanded jet flows. This investigation comprised the following: Study of the various resonance tube modes under a wide range of nozzle pressure, spacing between nozzle and tube mouth, and different tube length; the effects of these modes on the endwall pressure and gas temperature; flow visualization of both jet and tube flows by spark shadowgraph technique; and measurement of wave speed inside the tube by the laser-schlieren techniques. An extensive study of the free-jet flow was undertaken to explain important aspects of various modes of operation of resonance tube flows

    Techno-economic projections for advanced small solar thermal electric power plants to years 1990-2000

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    Advanced technologies applicable to solar thermal electric power systems in the 1990-200 time-frame are delineated for power applications that fulfill a wide spectrum of small power needs with primary emphasis on power ratings less than 10MWe. Projections of power system characteristics (energy and capital costs as a function of capacity factor) are made based on development of identified promising technologies and are used as the basis for comparing technology development options and combinations of these options to determine developmental directions offering potential for significant improvements. Stirling engines, Brayton/Rankine combined cycles and storage/transport concepts encompassing liquid metals, and reversible-reaction chemical systems are considered for two-axis tracking systems such as the central receiver or power tower concept and distributed parabolic dish receivers which can provide efficient low-cost solar energy collection while achieving high temperatures for efficient energy conversion. Pursuit of advanced technology across a broad front can result in post-1985 solar thermal systems having the potential of approaching the goal of competitiveness with conventional power systems

    Shear-Layer Flow Regimes and Wave Instabilities and Reattachment Lengths Downstream of an Abrupt Circular Channel Expansion

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    A n experimental investigation of water flow through an abrupt circular•-channel e

    An integrated analysis of molecular aberrations in NCI-60 cell lines

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    <p>Abstract</p> <p>Background</p> <p>Cancer is a complex disease where various types of molecular aberrations drive the development and progression of malignancies. Large-scale screenings of multiple types of molecular aberrations (e.g., mutations, copy number variations, DNA methylations, gene expressions) become increasingly important in the prognosis and study of cancer. Consequently, a computational model integrating multiple types of information is essential for the analysis of the comprehensive data.</p> <p>Results</p> <p>We propose an integrated modeling framework to identify the statistical and putative causal relations of various molecular aberrations and gene expressions in cancer. To reduce spurious associations among the massive number of probed features, we sequentially applied three layers of logistic regression models with increasing complexity and uncertainty regarding the possible mechanisms connecting molecular aberrations and gene expressions. Layer 1 models associate gene expressions with the molecular aberrations on the same loci. Layer 2 models associate expressions with the aberrations on different loci but have known mechanistic links. Layer 3 models associate expressions with nonlocal aberrations which have unknown mechanistic links. We applied the layered models to the integrated datasets of NCI-60 cancer cell lines and validated the results with large-scale statistical analysis. Furthermore, we discovered/reaffirmed the following prominent links: (1)Protein expressions are generally consistent with mRNA expressions. (2)Several gene expressions are modulated by composite local aberrations. For instance, CDKN2A expressions are repressed by either frame-shift mutations or DNA methylations. (3)Amplification of chromosome 6q in leukemia elevates the expression of MYB, and the downstream targets of MYB on other chromosomes are up-regulated accordingly. (4)Amplification of chromosome 3p and hypo-methylation of PAX3 together elevate MITF expression in melanoma, which up-regulates the downstream targets of MITF. (5)Mutations of TP53 are negatively associated with its direct target genes.</p> <p>Conclusions</p> <p>The analysis results on NCI-60 data justify the utility of the layered models for the incoming flow of cancer genomic data. Experimental validations on selected prominent links and application of the layered modeling framework to other integrated datasets will be carried out subsequently.</p
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